Major Depressive Disorder

• Males and females aged 18-55 years (inclusive)

• Must be generally healthy

• Must have a BMI range of 18.00-32.00kg/m2

• Must agree to use adequate contraception

• Must not have an anxiety disorder, bipolar disorder or depression and psychosis

• Must not smoke more than 5 cigarettes or equivalent nicotine-containing products per day, for 3 months prior to screening

• Must not have used psychedelics or hallucinogenic substances on more than 5 occasions

• Must not have first degree family history of a psychotic disorder (including schizophrenia, schizoaffective disorder, or bipolar disorder)

Oral tablets