Current Trials Archive

CM2420 Part B

Healthy Participants 15 nights in-house + 2 visits

Study Focus:
Non-alcoholic Steatohepatitis
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 30kg/m²
Body weight must be between 45 to 100kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 1 month prior
No significant allergies
Non-Smokers
No dietary requirements

CM6521

New

Healthy Participants 15 nights + 2 follow up visits

Study Focus:
Rheumatoid Arthritis & NASH
Administration:
Oral Capsules
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 32kg/m²
Body weight must be above 50kg
Must be in good general health
Must not be taking any medications
No significant allergies
No blood donation 3 months prior
Non-smokers
No dietary requirements

CM5221

New

Healthy Participants 21 nights in house + 1 follow up visit + 1 phone call

Study Focus:
Thyroid Cancer
Administration:
Oral Capsules
Eligibility Requirements:

Males and females aged 18 to 55 years
Females must be of non-childbearing potential (postmenopausal or surgically sterile)
BMI must be between 18.5 to 30kg/m²
Must be in good general health
Must not be taking any medications
No significant allergies
No blood donation 2 months prior
Non-smokers

CM5521

New

Participants with Atopic Dermatitis 8 Visits and twice daily brief video calls over approximately 1 month

Study Focus:
Atopic Dermatitis (Eczema)
Administration:
Topical Gel
Eligibility Requirements:

Males and females aged 18 years and above
Must have been diagnosed with moderate to severe Atopic Dermatitis
Body weight must be above 40kg
Medication criteria applies
No significant allergies

CM8920 Part B

Healthy Participants 17 nights in-house + 1 visit

Study Focus:
Inflammatory Bowel Diseases
Administration:
Oral Tablet
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 32kg/m²
Body weight must be above 55kg
Must be in good general health
Must not be taking any medications
No significant allergies
No blood donation 1 month prior
Non-smokers
No dietary requirements

CM0420 Part B

Healthy Participants 2 nights in-house + 12 visits

Study Focus:
Auto-Immune Diseases
Administration:
Injection
Eligibility Requirements:

Males and females aged 18 to 55 years
Body weight must be between 40 to 120kg
Must be in good general health
Must not be taking any medications
No significant allergies
Social smokers allowed

CM4821

New

Healthy Participants 4 x periods (4 nights + 5 visits each + 1 additional visit in period 4)

Study Focus:
Myeloid Malignancies
Administration:
Oral Capsule
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 32kg/m²
Body weight must be between 55 – 100kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 2 months prior
Non-smokers
No dietary requirements

CM6321

New

Healthy Participants 2 in-house stays (8 nights each) + 5 Visits

Study Focus:
Non-Alcoholic Fatty Liver Disease
Administration:
Oral Tablet and Subcutaneous Injection
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 28 to 40kg/m²
Must be in good general health
Must not be taking any medications (other than contraception)
No significant allergies
No blood donation 3 months prior
Non-smokers
No dietary requirements

CM6621

New

Healthy Participants 9 nights in-house

Study Focus:
Irritable Bowel Syndrome
Administration:
Oral Tablet
Eligibility Requirements:

Males and females aged 18 to 59 years
BMI must be between 18.5 to 30kg/m²
Females: Body weight must be above 45kg
Males: Body weight must be above 50kg
Must be in good general health
Must not be taking any medications (other than contraception)
No significant allergies
No blood donation 2 months prior
Non-smokers
No dietary requirements

CM5421

New

Healthy Participants 7 nights in-house + 1 additional night

Study Focus:
Dementia
Administration:
Oral Solution
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 32kg/m²
Body weight must be above 45kg
Must be in good general health
Must not be taking any medications (other than contraception)
No significant allergies
Light smokers allowed

CM2620

New

Healthy Participants 2 nights in-house + 1 visit

Study Focus:

Administration:

Eligibility Requirements:

Males and females aged 18 to 64 years
BMI must be between 18.5 to 30kg/m²
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donations 1 month prior
No significant allergies
Non-smokers

CM9820

Healthy Participants 5 nights in-house + 1 phone call

Study Focus:
Narcolepsy
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 32kg/m²
Body weight must be above 50kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 2 months prior
No significant allergies
Non-Smokers
No dietary requirements

CM4621 Part B

Healthy Participants 12 nights in-house + 1 visit

Study Focus:
Inflammatory Bowel Disease
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 65 years
Females must be of non-childbearing potential (surgically sterile or post-menopausal)
BMI must be between 18 to 32kg/m²
Must be in good general health
Must not be taking any medications
No significant allergies
Non-Smokers

CM9320

Healthy Participants 17 nights in-house

Study Focus:
Antibiotic Resistance
Administration:
IV
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18.5 to 29.9kg/m²
Body weight must be between 55 to 100kg
Females must be of non-child bearing potential (surgically sterile or post-menopausal)
Must be in good general health
Must not be taking any medications
No blood donation 2 months prior
No significant allergies
Light smokers allowed
No dietary requirements

CM4120

Healthy Participants 3 nights in-house + 1 visit

Study Focus:
Type II Diabetes
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 32kg/m²
Must be in good general health
Must not be taking any medications
No blood donation 3 months prior
No significant allergies
Light smokers allowed
No dietary requirements

CM1520 Part B

Healthy Participants 9 nights in-house + 1 visit

Study Focus:
Auto-Immune Diseases (Such as Psoriasis)
Administration:
Oral Solution
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 30kg/m²
Body weight must be above 50kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 3 months prior
No significant allergies
Non-Smokers

CM4721

Healthy Participants 21 nights in-house + 1 visit

Study Focus:
Inflammatory Diseases
Administration:
Oral Tablet
Eligibility Requirements:

Males and females aged 18 to 45 years
BMI must be between 19 to 30kg/m²
Must be in good general health
Must not be taking any medications
No blood donation 2 months prior
No significant allergies
Non-Smokers
No dietary requirements

CM4020 Part B

Healthy Participants 17 nights in-house + 1 visit

Study Focus:
Lysosomal Storage Disorders
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 30kg/m²
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 3 months prior
No significant allergies
Non-Smokers

CM2820

Healthy Participants 3 nights in-house + 1 visit

Study Focus:
Nonalcoholic Steatohepatitis
Administration:
Oral Capsule
Eligibility Requirements:

Males and females aged 18 to 65 years
Females must be of non-childbearing potential
BMI must be between 18 to 32kg/m²
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 2 months prior
No significant allergies
Non-Smokers

CM5021

Healthy Participants 20 nights in-house + 1 visit

Study Focus:
Auto-Immune Diseases
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 60 years
BMI must be between 18 to 30kg/m²
Must be in good general health
Must not be taking any medications
No blood donation 3 months prior
No significant allergies
Non-Smokers

CM5121

Healthy Participants 3 nights in-house + 1 phone call

Study Focus:
Depression
Administration:
Capsules
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 32kg/m²
Body weight must be above 50kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 2 months prior
No significant allergies
Non-Smokers

CM3820

Healthy Participants 30 nights in-house + 1 visit

Study Focus:
Serious Infections
Administration:
Oral Tablet
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 30kg/m²
Body weight must be between 40 to 100kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 1 month prior
No significant allergies
Non-Smokers

CM3620

Healthy Participants 5 nights in-house + 1 visit

Study Focus:
Pulmonary Arterial Hypertension
Administration:
Inhalation
Eligibility Requirements:

Males and females aged 18 to 60 years
BMI must be between 18 to 32kg/m²
Body weight must be 50kg or above
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 3 months prior
No significant allergies
Non-Smokers

CM0120

Participants with High Cholesterol 19 visits

Study Focus:
High Cholesterol
Administration:
Subcutaneous Injection
Eligibility Requirements:

Males and females aged 18 to 65 years
Females must be of non-childbearing potential
BMI must be between 18 to 32kg/m²
Must have elevated lipoprotein(a) (high cholesterol)
Medication criteria applies
No blood donation 2 months prior
No significant allergies
Non-Smokers

CM1220

Healthy Participants 2 nights in-house + 1 visit

Study Focus:
Spinal Cord Injury
Administration:
Subcutaneous Injection
Eligibility Requirements:

Females aged 18 to 65 years
BMI must be between 18 to 33kg/m²
Body weight must be above 50kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 1 week prior
No significant allergies
Light smokers allowed

CM4621

Healthy Participants 3 nights in-house + 1 visit

Study Focus:
Inflammatory Bowel Disease
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 65 years
Females must be of non-childbearing potential (surgically sterile or post-menopausal)
BMI must be between 18 to 32kg/m²
Must be in good general health
Must not be taking any medications
No significant allergies
Non-Smokers

CM4921

Healthy Participants 11 night's in-house + 3 Visits

Study Focus:
Chronic Pain
Administration:
Oral Capsule
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 32kg/m²
Body weight must be above 50kg
Must be in good general health
Must not be taking any medications (other than contraception)
No significant allergies
Non-Smokers
No dietary requirements

CM2420

Healthy Participants 2 nights in-house + 2 visits

Study Focus:
Non-alcoholic Steatohepatitis
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 30kg/m²
Body weight must be between 45 to 100kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 1 month prior
No significant allergies
Non-Smokers
No dietary requirements

CM2520 Part A

Healthy Participants 4 nights in-house + 5 visits

Study Focus:
Alzheimer's Disease
Administration:
IV Infusion
Eligibility Requirements:

Males and females aged 18 to 45 years
BMI must be between 19 to 32kg/m²
Body weight must be between 45 to 100kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 3 months prior
No significant allergies
Non-Smokers

CM8420 P3

Healthy Participants 2 in-house stays (3 nights each)

Study Focus:
Frontotemporal Dementia
Administration:
Oral
Eligibility Requirements:

Males and females aged 18 to 55 years
BMI must be between 18 to 30kg/m²
Body weight must be between 50 to 120kg
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 2 months prior
No significant allergies
Non-smokers
No dietary requirements

CM1020

Healthy Participants 3 nights in-house + 10 visits

Study Focus:
Acromegaly
Administration:
Subcutaneous Injection
Eligibility Requirements:

Males only 18 to 50 years
BMI must be between 19 to 30 kg/m²
Body weight must be at least 50kg
Must be in good general health
Must not be taking any medications
No blood donation 2 months prior
No significant allergies
Non-Smokers

CM1120

Healthy Participants 4 nights in-house + 12 visits

Study Focus:
Parkinson's Disease
Administration:
Injection
Eligibility Requirements:

Males and females aged 18 to 65 years
BMI must be between 18 to 30kg/m²
Must be in good general health
Must not be taking any medications (other than contraception)
No blood donation 3 months prior
No significant allergies
Non-Smokers
No dietary requirements

CM0420

Healthy Participants 4 nights in-house + 4 visits

Study Focus:
Auto-Immune Diseases
Administration:
Injection
Eligibility Requirements:

Males and females aged 18 to 55 years
Body weight must be between 40 to 120kg
Must be in good general health
Must not be taking any medications
No significant allergies
Social smokers allowed

Current Trials

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OUR CURRENT TRIALS

CM2420 Part B

CM6521

CM5221

CM5521

CM8920 Part B

CM0420 Part B

CM4821

CM6321

CM6621

CM5421

CM2620

CM9820

CM4621 Part B

CM9320

CM4120

CM1520 Part B

CM4721

CM4020 Part B

CM2820

CM5021

CM5121

CM3820

CM3620

CM0120

CM1220

CM4621

CM4921

CM2420

CM2520 Part A

CM8420 P3

CM1020

CM1120

CM0420

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