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CM5221

New
Healthy Participants 21 nights in house + 1 follow up visit + 1 phone call
Study Focus:
Thyroid Cancer
Administration:
Oral Capsules
Eligibility Requirements:
  • Males and females aged 18 to 55 years
  • Females must be of non-childbearing potential (postmenopausal or surgically sterile)
  • BMI must be between 18.5 to 30kg/m²
  • Must be in good general health
  • Must not be taking any medications
  • No significant allergies
  • No blood donation 2 months prior
  • Non-smokers
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CM0420 Part B

Healthy Participants 2 nights in-house + 12 visits
Study Focus:
Auto-Immune Diseases
Administration:
Injection
Eligibility Requirements:
  • Males and females aged 18 to 55 years
  • Body weight must be between 40 to 120kg
  • Must be in good general health
  • Must not be taking any medications
  • No significant allergies
  • Social smokers allowed
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CM4821

New
Healthy Participants 4 x periods (4 nights + 5 visits each + 1 additional visit in period 4)
Study Focus:
Myeloid Malignancies
Administration:
Oral Capsule
Eligibility Requirements:
  • Males and females aged 18 to 65 years
  • BMI must be between 18 to 32kg/m²
  • Body weight must be between 55 – 100kg
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 2 months prior
  • Non-smokers
  • No dietary requirements
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CM2620

New
Healthy Participants 2 nights in-house + 1 visit
Study Focus:

Administration:

Eligibility Requirements:
  • Males and females aged 18 to 64 years
  • BMI must be between 18.5 to 30kg/m²
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donations 1 month prior
  • No significant allergies
  • Non-smokers
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CM9820

Healthy Participants 5 nights in-house + 1 phone call
Study Focus:
Narcolepsy
Administration:
Oral
Eligibility Requirements:
  • Males and females aged 18 to 55 years
  • BMI must be between 18 to 32kg/m²
  • Body weight must be above 50kg
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 2 months prior
  • No significant allergies
  • Non-Smokers
  • No dietary requirements
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CM4120

Healthy Participants 3 nights in-house + 1 visit
Study Focus:
Type II Diabetes
Administration:
Oral
Eligibility Requirements:
  • Males and females aged 18 to 65 years
  • BMI must be between 18 to 32kg/m²
  • Must be in good general health
  • Must not be taking any medications
  • No blood donation 3 months prior
  • No significant allergies
  • Light smokers allowed
  • No dietary requirements
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CM2820

Healthy Participants 3 nights in-house + 1 visit
Study Focus:
Nonalcoholic Steatohepatitis
Administration:
Oral Capsule
Eligibility Requirements:
  • Males and females aged 18 to 65 years
  • Females must be of non-childbearing potential
  • BMI must be between 18 to 32kg/m²
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 2 months prior
  • No significant allergies
  • Non-Smokers
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CM5121

Healthy Participants 3 nights in-house + 1 phone call
Study Focus:
Depression
Administration:
Capsules
Eligibility Requirements:
  • Males and females aged 18 to 55 years
  • BMI must be between 18 to 32kg/m²
  • Body weight must be above 50kg
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 2 months prior
  • No significant allergies
  • Non-Smokers
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CM3620

Healthy Participants 5 nights in-house + 1 visit
Study Focus:
Pulmonary Arterial Hypertension
Administration:
Inhalation
Eligibility Requirements:
  • Males and females aged 18 to 60 years
  • BMI must be between 18 to 32kg/m²
  • Body weight must be 50kg or above
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 3 months prior
  • No significant allergies
  • Non-Smokers
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CM1220

Healthy Participants 2 nights in-house + 1 visit
Study Focus:
Spinal Cord Injury
Administration:
Subcutaneous Injection
Eligibility Requirements:
  • Females aged 18 to 65 years
  • BMI must be between 18 to 33kg/m²
  • Body weight must be above 50kg
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 1 week prior
  • No significant allergies
  • Light smokers allowed
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CM4621

Healthy Participants 3 nights in-house + 1 visit
Study Focus:
Inflammatory Bowel Disease
Administration:
Oral
Eligibility Requirements:
  • Males and females aged 18 to 65 years
  • Females must be of non-childbearing potential (surgically sterile or post-menopausal)
  • BMI must be between 18 to 32kg/m²
  • Must be in good general health
  • Must not be taking any medications
  • No significant allergies
  • Non-Smokers
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CM2420

Healthy Participants 2 nights in-house + 2 visits
Study Focus:
Non-alcoholic Steatohepatitis
Administration:
Oral
Eligibility Requirements:
  • Males and females aged 18 to 55 years
  • BMI must be between 18 to 30kg/m²
  • Body weight must be between 45 to 100kg
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 1 month prior
  • No significant allergies
  • Non-Smokers
  • No dietary requirements
Read More

CM2520 Part A

Healthy Participants 4 nights in-house + 5 visits
Study Focus:
Alzheimer's Disease
Administration:
IV Infusion
Eligibility Requirements:
  • Males and females aged 18 to 45 years
  • BMI must be between 19 to 32kg/m²
  • Body weight must be between 45 to 100kg
  • Must be in good general health
  • Must not be taking any medications (other than contraception)
  • No blood donation 3 months prior
  • No significant allergies
  • Non-Smokers
Read More

CM1020

Healthy Participants 3 nights in-house + 10 visits
Study Focus:
Acromegaly
Administration:
Subcutaneous Injection
Eligibility Requirements:
  • Males only 18 to 50 years
  • BMI must be between 19 to 30 kg/m²
  • Body weight must be at least 50kg
  • Must be in good general health
  • Must not be taking any medications
  • No blood donation 2 months prior
  • No significant allergies
  • Non-Smokers
Read More

CM0420

Healthy Participants 4 nights in-house + 4 visits
Study Focus:
Auto-Immune Diseases
Administration:
Injection
Eligibility Requirements:
  • Males and females aged 18 to 55 years
  • Body weight must be between 40 to 120kg
  • Must be in good general health
  • Must not be taking any medications
  • No significant allergies
  • Social smokers allowed
Read More

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